Application

Application Hero

From Living Cell Therapies to Next-Generation Biologics

CellShot® enables non-destructive gene delivery across a broad spectrum of applications—from CRISPR-edited immune cells and RNA-based CAR therapies to advanced biologics manufacturing platforms.

Designed for living systems, CellShot bridges discovery, manufacturing, and clinical translation.

Cell & Gene Therapy Manufacturing

Building the Foundation for Next-Generation Cell & Gene Therapies

CellShot® ND-FFT technology is designed as a manufacturing-grade foundation for cell and gene therapies.

By integrating non-viral gene delivery, high cellular viability and expandability, and scalable manufacturing, CellShot enables cell engineering processes that remain robust throughout clinical manufacturing.

The 3 Pillars of the CGT Sector

Non-viral Gene Delivery
Non-viral Gene Delivery

Core pillar of the platform, providing capabilities beyond viral vectors. It enables precise gene suppression or deletion and insertion into safe genomic loci.

High Viability & Expandability

Sets CellShot® apart from conventional methods. It minimizes damage while preserving proliferation capacity, supporting robust expansion.

High Viability
Scalable Manufacturing
Scalable Manufacturing

From R&D to large-scale GMP production, flow electroporation enables seamless adjustment of throughput without altering conditions.

CGT Modalities Enabled by CellShot®

From genome editing to repeatable cell programming

  • CRISPR-edited T cells / NK cells
  • mRNA CAR-T / CAR-NK
  • Multi-gene / sequential editing
  • Repeated transfection workflows
CGT Modalities

Our Solution

CellShot delivers safe, scalable, and damage-free nonviral gene transfer.

The 3 Applications of the CGT Sector

Manufacturing-grade CRISPR Edition
Asynchronized, Repeatable, Non-viral CRISPR EP
Asynchronized, Repeatable, Non-viral CRISPR EP

CRISPR KO/KI workflows optimized for cell fitness and scalable manufacturing.

  • Sequential KO/KI
  • Repeated EP without loss of viability
RNA-based Transient Cell Programming
Multigenic mRNA EP with low-DMSO recovery
Multigenic mRNA EP with low-DMSO recovery

Transient RNA delivery enables fine-tuned immune modulation.

  • mRNA CAR expression
  • Transient RNA silencing
High-throughput Applications
MSC / iPSC / Immune cell workflows
MSC / iPSC / Immune cell workflows

Scalable flow-based EP enables consistent cell processing.

  • Transient mRNA programming
  • Differentiation priming

The Future Applications of the Biologics Sector

Next-Generation Biologics Manufacturing
Downstream cost & quality optimization
Downstream cost & quality optimization

PFEP-assisted delivery improves AAV assembly efficiency.

  • Improved packaging efficiency
  • Reduced polishing burden
Adjunct Immuno-engineering Strategies
Safeguarding on-target activity
Safeguarding on-target activity

Concept-stage development of bispecific strategies.

  • Complementary to cell engineering
  • Enhancing safety profiles
Background

Application Spectrum: From Cell Therapies to Next-Gen Biologics

CRISPR KO/KI

CRISPR KO/KI

Precision genome editing

RNA-Multigenic Thearpy

RNA-Multigenic Thearpy

Immune cell programming

MSC/iPSC RNA

MSC/iPSC RNA

Non-integrating modulation

AAV

AAV

Biologics manufacturing

Bi-Abs

Bi-Abs

Safety-oriented modulation